产品货号：
Z12542
中文名称：
BTK抗体
英文名称：
Anti-BTK Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BTK Antibody |
| 指标别名 | AGMX1;AT;ATK;B cell progenitor kinase;BPK;Bruton tyrosine kinase;BTK;IMD1;PSCTK1;Tyrosine protein kinase BTK;XLA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,ICC,IF |
| 基因名称 | BTK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | BTK antibody was raised against a synthetic peptide corresponding to 16 amino acids near the amino-terminus of human BTK.The immunogen is located within amino acids 20 - 70 of BTK. |
| 计算分子量 | 76kDa |
| 成分 | BTK Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | BTK Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Bruton's tyrosine kinase (BTK) was initially identified as a member of the src family for protein-tyrosine kinases that was involved in X-linked agamma-globulinaemia,and has since been shown to involved in a number of signaling pathways in hemapoietic lineage.It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4,6,8,and 9.The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens.BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88,TIRAP,and IRAK,but not TRAF-6,suggesting that BTK is involved in lipopolysaccharide signal transduction. |
| Uniprot ID | Q06187 |
| 基因名全称 | Bruton agammaglobulinemia tyrosine kinase |
| 蛋白名全称 | Bruton agammaglobulinemia tyrosine kinase |
| 推荐稀释比 | BTK antibody can be used for the detection of BTK by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL and immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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